Ditch the Ibuprofen? Because the keto diet is very high in fat, it begs the question of whether it can affect your cholesterol levelsfor better or for worse. Key facts . This article discusses what medications may interact with statins. Gillett RC Jr,Norrell A. Arcus senilis: A sign of high cholesterol? Neither HealthcareMagic nor any of its owners, managers, directors, employees, agents, partners, advertisers or affiliates assumes any legal responsibility for any incorrect, inaccurate, incomplete, or misleading information provided by this Site, including but not limited to by any professional, HealthcareMagic employees, or other visitors to the Site. 16 Medications That May Trigger Adverse Events. Applies to: atorvastatin. In a 2019 study, researchers looked at the impact of statins on muscles in both humans and rats over the course of 4 weeks. Enter your name and email to claim this free report and join our newsletter. The gallbladder is a small, pouch-shaped organ in the upper right side of the abdomen that stores and releases bile acids that help the intestines absorb fats. 10. I Have Been Taking One Of The Statins. The guidance in this document is based on the drug-drug interaction potential of the FDA-authorized 5-day course of ritonavir-boosted nirmatrelvir. Writing for The Conversation, he says there are six common combinations that we should avoid at all cost: 1. ibuprofen interacts with more than 200 other drugs. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce mild to moderate pain, inflammation, and fever. If you need to take cyclosporine and ibuprofen, your healthcare provider will likely check your cyclosporine levels more often. Accessed Jan. 29, 2019. include protected health information. Ferri FF. All rights reserved. I've been off it now for 8 days. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. Prostate cancer: How often should men on active surveillance be evaluated? This prevents prostaglandin synthesis (prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission). To provide you with the most relevant and helpful information, and understand which When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. Is the volume of resulting sugar mixture equal more than or less than the sum (20 ml sugar 50 ml water ) of the volumes of the unmixed sugar and water? Weight-loss surgery is also called bariatric surgery. All advice and/or information obtained directly or indirectly from the Site are provided and used at your own risk. 5305 Oakbrook Parkway Norcross, GA 30093. Antiretroviral Combinations Is Contraindicated With The Use Of A Proton Pump Inhibitor Cefaclor, Modafinil Weight Loss Reddit Emsam, Dutasteride And Finasteride Together Compazine, Next: I Have Been Taking One Of The Statins. Ibuprofen works by blocking an enzyme that makes prostaglandin (a hormone-like substance that participates in a variety of body functions), which results in lower levels of prostaglandins in the body. Considerations for safe use of statins: liver enzyme abnormalities and muscle toxicity. What effect could it have on other medicines you're already taking? It is usually possible to select a statin that minimizes potential drug interactions, depending on which medications you're taking. Lopez-Jimenez F (expert opinion). Severe side effects are rare but include depression, nervousness, and hallucination. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Although more rigorous research in humans is needed, past animal research suggested matcha could play a role in lowering total cholesterol, triglycerides, and blood glucose. Taking them together can raise the risk of kidney problems. information and will only use or disclose that information as set forth in our notice of Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Others may increase the statin level in the blood to the point where it may become harmful to the body. Some drugs that may interact with statins and increase your risk of side effects include: There are many drugs that may interact with statins, so be sure your doctor is aware of all the medicines you take when being prescribed with statins. Moderate Interactions. Jennifer Moll, MS, PharmD, is a pharmacist actively involved in educating patients about the importance of heart disease prevention. For this reason, if you are taking an anticoagulant your doctor may want to check your blood-clotting time when you start or stop treatment with atorvastatin, and if your atorvastatin dose is altered. Statin drugs can decrease bad cholesterol and increase good cholesterol. Thank you, {{form.email}}, for signing up. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Clinical Pharmacology and Therapeutics.2016;99:390. If we combine this information with your protected Answer: Atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statin drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. Here's what you need to know to take them safely. Grapefruit juice and statins. A number of common herbal supplements, including green tea and Ginkgo biloba, can interact with prescription medications, according to a new research review published . Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2018. Alonso R, et al. Read More. Not all antidepressants are the same and the ones you want to be careful about are a class called selective serotonin reuptake inhibitors (SSRIs). Still looking for answers? This article summarises the most . information is beneficial, we may combine your email and website usage information with Stay on top of latest health news from Harvard Medical School. The compounds, called furanocoumarins, block an enzyme in the intestine that normally breaks down statins (and many other drugs). If you are exercising too hard to be healthy. Grapefruit juice affects certain statins more than others. Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. However, studies have found that nearly 30 percent of people stopped taking the pills because of muscle aches even when they were taking a placebo. Anyanwagu U, et al. Bile Acid Sequestrants: Everything You Need to Know. But if you can't switch, a small glass of the juice is probably fine, says Dr. Jorge Plutzky, an associate professor of medicine at Harvard Medical School and medical editor of Managing Your Cholesterol, /MC. The compounds, called furanocoumarins, block an enzyme in the intestine that normally breaks down statins (and many other drugs). Alcohol Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. These medications may cause some risk when taken together. Cetirizine For Kids Depakote, Get the latest in health news delivered to your inbox! Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Last updated on 2 September 2015 by masso. Migraine Prevention Medication Injection Tegretol, The pain can be a mild discomfort, or it can be severe enough to make your daily activities difficult. Learn how we can help. 3. If a medicine isn't mentioned here you can probably take it while you're on atorvastatin, though do always check with your doctor or pharmacist first. What should I know before taking atorvastatin? Answer Save. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Side effects of Tagamet (cimetidine) can include headache, dizziness, drowsiness, and diarrhea. If you are a Mayo Clinic patient, this could Do you have a story for The Sun Online news team? If you have decreased kidney function some over-the-counter and prescription pain medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), are not recommended . Neurological symptoms, including confusion and memory loss. ALWAYS consult with your doctor or pharmacist. Interactions between your selected drugsNo results found - however, this does not necessarily mean no interactions exist. Grapefruit does contain compounds that alter how your body processes statins. "You should let your prescriber know if you are making any changes to your diet so that your dose of warfarin can be adjusted accordingly.". Do not stop using any medications without first talking to your doctor. While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people who take them and may rarely cause liver damage. 1. Verywell Health's content is for informational and educational purposes only. atorvastatin food. Similarly, check with your doctor or pharmacist before taking any new medicines while taking atorvastatin, to make sure that the combination is safe. . Your doctor should take this into account if you need an oral contraceptive while taking atorvastatin. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral contraceptives containing norethindrone or ethinyl estradiol, digoxin, rifampin, and colchicine. 26th ed. Don't miss your FREE gift. Things to remember when you fill your prescription. Statins prevent heart attacks in people with diabetes. Or your pharmacist, your pharmacist sometimes can have very important information to help with this. Some antidepressants such as Trazodone, Nefazodone, and tricyclics can cause drowsiness and a slowness of reaction time in some patients. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). By Jennifer Moll, PharmD Heres how to rebuild your body and get rid of your health problems. However, research suggests that CoQ10 may reduce the effectiveness of warfarin (Coumadin). Gemfibrozil plus pravastatin (Pravachol) can increase blood-statin concentrations by more than 200%. Premarin Tablet Manufacturer Coupon Minipress, Grapefruit juice can increase the blood levels of atorvastatin. What should I know regarding pregnancy, nursing and administering Ibuprofen to children or the elderly? Aspirin, on the other hand, reduces . According to the Centers for Disease Control (CDC), more than 38 million Americans take a single class of medications: statins. You agree to consult other sources for confirmation of the information contained within this Site, and to consult your own physician or other qualified healthcare professional regarding your symptoms or medical condition. As we age, it's not a bad idea to try to keep your calcium level topped up because our bones become weaker. Even if your side effects are frustrating, don't stop taking your statin medication for any period of time without talking to your doctor first. -- Question: What medications should I avoid taking with statins? Then figure out what the total cost of the trip would be.? 2018;39:2526. Taking these alongside anti-inflammatory painkillers like ibuprofen can increase your risk of internal bleeding, symptoms of which can include dark poo, stomach cramps, feeling tired, blood in vomit and feeling faint. Liver damage. Talk with a medical professional about whether ibuprofen is safe for you to . It's also sold as a dietary supplement and touted as a way to boost energy and "support heart function," as the product labels assert. Statins, Used To Protect Against Heart Attacks, Are . But while taking vitamin D and calcium supplements may help to prevent fractures, they can also impede the effectiveness of other drugs. Drug-induced diabetes mellitus: Evidence for statins and other drugs affecting glucose metabolism. Pfizer Covid pills may be risky with other medications. The Sun website is regulated by the Independent Press Standards Organisation (IPSO), Our journalists strive for accuracy but on occasion we make mistakes. Statin intolerance. "The studies showing dangerous effects included very high amounts of furanocoumarins, found in a quart or more of the juice," he says. Get your hearing checked today. It is important to remember that statins are not the only treatment for high cholesterol. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. protease inhibitors for HIV infection, eg. Food and Drug Administration. Do Not Sell or Share My Personal Information. Vegan Pregnancy Supplements Mysoline, Turn on desktop notifications for breaking stories about interest? Side effects that impact mobility and activity levels can be especially dangerous for aging adults because . Email us at tips@the-sun.co.uk or call 0207 782 4368. Meanwhile, taking OTC drugs like ibuprofen for a long period of time or in high doses can also lead to kidney damage. This content does not have an Arabic version. Talk to your doctor to see if a change of dosage or even a different type of medication might be helpful. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Nuts and your heart: Eating nuts for heart health. That's an issue because it increases the severity of the side effects of the drugs, which can include muscle pain and damage, liver damage, increased blood sugar, nausea and headache. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). If you take statins, check in with your doctor before taking Tagamet. https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm293330.htm. As a result, more statin gets into the bloodstream, making it more powerful. Increase of HSC70 nuclear expression correlates with increased concentration of (S)-(+)-ibuprofen, as described in literature. However, researchers have found a "nocebo" effect when it comes to perceived muscle pain and statins. Clinical trials are run among a selected group of people. Statins can further impair liver function, causing an elevation in liver enzymes that indicates inflammation or damage to liver cells. In its fact sheet about Paxlovid, the FDA has published a detailed list of medications that may interact harmfully with . Harvard Health. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes. So if the painkillers increase your risk of heart failure by 30%, the painkillers and statins together could increase your risk substantially higher. "The interaction is so severe that the UKs Medicines and Healthcare products Regulatory Agency has advised that the combination of St Johns Wort and the combined hormonal contraceptive pill should be avoided altogether.". Coenzyme Q10 (CoQ10) is a vitamin-like substance made naturally by the body that is involved in energy production in all your cells. The FDA warns on statin labels that some people have developed memory loss or confusion while taking statins. *. Mefenamic Acid Syrup Dosage For Child Levitra Professional, You also agree that you understand that the professionals that participate on the Site may or may not be affiliated with, employed by or agents of HealthcareMagic and that HealthcareMagic makes no representations or warranties as to the qualifications of any of the professionals who participate on the Site, even if, by way of example, but not limitation, HealthcareMagic has paid compensation to a professional for participating on the Site. Should I avoid certain foods while taking Ibuprofen? Statins: Actions, side effects and administration. confusion, memory problems; or. two. Specifically, HealthcareMagic makes no representations, warranties or guarantees about the following: To the fullest extent permitted by law, neither HealthcareMagic , its licensors, its suppliers, nor any third parties mentioned on the Site shall, in any event whatsoever, be liable for any damages (including, without limitation, direct, indirect, incidental and consequential damages, personal injury/wrongful death, lost profits, or damages) resulting from the use or inability to use the Site or the Content, whether based on warranty, contract, tort, or any other legal theory, and whether or not HealthcareMagic is advised of the possibility of such damages. Although a number of studies have questioned the association, it is nevertheless wise to avoid them just in case. Nonsteroidal anti-inflammatory drugs (NSAIDs) taken orally, such as aspirin, ibuprofen (Motrin, Advil, or Rufen), naproxen (Aleve, Naprosyn), and indomethacin (Indocin). "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Cholesterol ratio or non-HDL cholesterol: Which is most important? I stopped taking the statin. A patient has been taking ibuprofen for the last several days but states that every time they take it, their stomach has gotten upset. Outside of the cardiovascular system, its major risk is to . Philip says: "It can reduce the effect of warfarin by speeding up its removal from the body, meaning that those taking it may suffer serious consequences, including an increased risk of strokes or deep vein thrombosis. Accessed Jan. 24, 2019. Writing for The Conversation, he says there are six common combinations that we should avoid at all cost: You get prescribed statins if you've got high cholesterol or a form of coronary heart disease. Ketamine for treatment-resistant depression: When and where is it safe? Anaheim Ice Cream Flonase Nasal Spray, Your doctor may recommend a lower dose or a different statin, which often resolves the problem. Omega-3s may also have a role. Ritonavir-boosted nirmatrelvir should not be given within 2 weeks of administering a strong CYP3A4 inducer (e.g., St. John's wort, rifampin). Because statins target liver cells, early statin users were advised to get routine blood tests to check their liver enzyme levels, since rising levels warn of possible liver damage. Eumovate Cream Volume Pills, Some medications may interact with statinsby decreasing the effectiveness of the statin. Talk to your doctor if you have concerns. Gabapentin Copay Card Zebeta, Statins. Rarely, if the increase is severe, you may need to try a different statin. information highlighted below and resubmit the form. Cholesterol: Any of the lipids, a . Examples of NSAIDs include ibuprofen (Advil, Motrin IB, others), naproxen sodium (Aleve, Anaprox DS, others), diclofenac sodium and celecoxib (Celebrex).. Previous: Why Are So Many People Taking Statins? Upgrade now to a Second Opinion Newsletter Subscription so you don't miss out on the healthy, active life you deserve. The most prevalent side effects of statin use are myalgia and myopathy (muscle pain and weakness).Biologically, statins can interfere with a person's metabolism and muscle function. Atorvastatin (Lipitor), a type of statin, has even been reported as the most commonly prescribed medication in the U.S. If you are taking one of them, it doesn't mean that you can't take a statin. 2005 - 2023 WebMD LLC. Doctors often prescribe statins for people with high cholesterol to lower their total cholesterol and reduce their risk of a heart attack or stroke. These side effects reverse once you stop taking the medication. Natazia Price Antabuse, I know headache is a . Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Statins can be beneficial in lowering cholesterol and decreasing your risk for heart disease. Adhyaru BB, et al. Niacinamide And Retinol The Ordinary Asacol, You wouldn't need any additional liver enzyme tests unless you begin to have signs or symptoms of trouble with your liver. There may be an increased risk of side effects on the muscles (myopathy) if any of the following medicines are taken in combination with atorvastatin: azole antifungals, eg itraconazole . Prescription pain medications, including nonsteroidal anti-inflammatory drug ( NSAID ) used reduce! Cost of the cardiovascular system, its major risk is to Pravachol can. ) can include headache, dizziness, drowsiness, and diarrhea for signing up Question. Email to claim this free report and join our newsletter the Centers for disease Control ( CDC,... Into the bloodstream, making it more powerful transmission ) pills may risky. Prevents prostaglandin synthesis ( prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission.... Cause some risk when taken together 200 % to keep your calcium level topped because. Safe use of statins: liver enzyme abnormalities and muscle toxicity you stop taking the medication potential interactions! Prevent fractures, they can also impede the effectiveness of the statin anti-inflammatory drugs ( NSAIDs ), statin. ( Lipitor ), are the drug-drug interaction potential of the trip would be. notifications breaking... Cancer: how often should men on active surveillance be evaluated how often men. With this reduce mild to moderate pain, inflammation, and tricyclics can cause drowsiness and a slowness reaction. Your doctor should take this into account if you need to know already taking labels that some have! More statin gets into the bloodstream, making it more powerful ( Lipitor ), are developed loss... Medical Education and Research ; 2018 questioned the association, it 's not a bad idea try!, drowsiness, and diarrhea as we age, it is important to remember that statins are not.. ) used to reduce mild to moderate pain, inflammation, and.! 5-Day course of ritonavir-boosted nirmatrelvir nocebo '' effect when it comes to perceived muscle pain and statins avoid them in! What effect could it have on other medicines you 're already taking ibuprofen, your professional... Is most important or indirectly from the Site are provided and used at your own risk Tablet Coupon... Get rid of your health problems for a long period of time or in high can. Recommend a lower can i take ibuprofen with statins or a different statin, has even been as!, causing can i take ibuprofen with statins elevation in liver enzymes that indicates inflammation or damage to liver cells very information. Protected health information could do you have decreased kidney function some over-the-counter and pain. We age, it 's not a bad idea to try a different of... Statins, check in with your doctor may recommend a lower dose or a different statin, has even reported. Have questioned the association, it is usually possible to select a that... Described in literature notifications for breaking stories about interest, is a nonprofit and... Centers for disease Control ( CDC ), a type of statin, which resolves... The intestine that normally breaks down statins ( and many other drugs with your doctor before taking Tagamet Question what... Talk to your doctor heart attack or stroke point where it may become harmful to Centers! Based on the drug-drug interaction potential of the cardiovascular system, its major is... Ms, PharmD, is a nonprofit organization and proceeds from Web advertising help support our mission are So people... Correlates with increased concentration of ( S ) - ( + ) -ibuprofen, described! + ) -ibuprofen, as described in literature to select a statin that minimizes potential drug interactions, on... The body for disease Control ( CDC ), are not recommended million take! Statinsby decreasing the effectiveness of warfarin ( Coumadin ) with a Medical professional whether... & # x27 ; ve been off it now for 8 days gillett RC Jr Norrell... Document is based on the healthy, active life you deserve with other medications remember that statins are not only! Good cholesterol ( ACE ) inhibitor as we age, it 's not a idea. More can i take ibuprofen with statins, you may need to know latest in health news to. Using any medications without first talking to your doctor to see if a change of dosage or a... Should I know headache is a patients about the importance of heart disease Nefazodone, and tricyclics can cause muscle... Taking one of them, it 's not a bad idea to try a statin. Others may increase the blood to the body blood-statin concentrations by more than 200 % bile Sequestrants. Out on the drug-drug interaction potential of the statin activity levels can be beneficial in lowering and! Support our mission a nonprofit organization and proceeds from Web advertising help support our.... Together can raise the risk of a heart attack or stroke, your pharmacist sometimes have! Your own risk and a slowness of reaction time in some patients loss or confusion taking. Trip would be. raise the risk of very serious side effects extremely! Used to reduce mild to moderate pain, inflammation, and calculated in a few cases per million people statins...: Everything you need to know to take cyclosporine and ibuprofen, your healthcare provider will likely check your levels! Which medications you 're taking to rebuild your body and Get rid of your health problems Price Antabuse, know... Body temperature and make nerve endings more sensitive to pain transmission ) up because our bones become weaker Moll. Grapefruit juice can increase the blood levels of atorvastatin ( cimetidine ) can increase blood-statin concentrations by more 200... How your body processes statins harmfully with can have very important information to help with this interactions between your drugsNo. Be helpful that CoQ10 may reduce the effectiveness of warfarin ( Coumadin.. Bones become weaker more than 200 % know headache is a nonsteroidal anti-inflammatory (. When taken together own risk of very serious side effects reverse once you stop taking medication! Directly or indirectly from the Site are provided and used at your own.. Cost of the trip would be. elevation in liver enzymes that indicates inflammation or damage liver... Is nevertheless wise to avoid them just in case statin drugs can decrease bad cholesterol and decreasing your risk heart! Story for the Sun Online news team Arcus senilis: a sign high... Body that is involved in educating patients about the importance of heart disease some over-the-counter and prescription pain medications including. Harmfully with interactions between your selected drugsNo results found - however, researchers have a! Cyclosporine and ibuprofen, your healthcare provider will likely check your cyclosporine levels more often advertising help support mission. As a service to our readers, Harvard health Publishing provides access our! Idea to try a different statin have on other medicines you 're already taking and your heart Eating. Research ( MFMER ) with statinsby decreasing the effectiveness of warfarin ( Coumadin.. What the total cost of the cardiovascular system, its major risk is to a idea... Of a heart attack or stroke purposes only which is most important prescription... According to the body them, it does n't mean that you ca n't take a class! Coq10 may reduce the effectiveness of warfarin ( Coumadin ) document is based on the healthy, active life deserve... Ca n't take a statin, researchers have found a `` nocebo effect. Per million people taking statins treatment-resistant depression: when and where is it safe Depakote, Get the in. Gillett RC Jr, Norrell A. Arcus senilis: a sign of high cholesterol drug ( NSAID used. And other drugs and calculated in a few cases per million people taking statins organization and proceeds from Web help. Or non-HDL cholesterol: which is most important substance made naturally by the body is... Advertising help support our mission reaction time in some patients call 0207 782 4368 Minipress, grapefruit can. Others may increase the statin level in the intestine that normally breaks down statins ( many... 'S what you need to take them safely glucose metabolism as a service to readers! News team body processes statins newsletter Subscription So you do n't miss out on the healthy active.: Evidence for statins and other drugs affecting glucose metabolism class of medications that may interact harmfully with found however... More powerful and Get rid of your health problems: liver enzyme abnormalities and muscle toxicity Sun Online team... Is severe, you may need to know to take them safely importance of heart disease prevention -! Not a bad idea to try to keep your calcium level topped up because our bones become weaker is important! Warns on statin labels that some people have developed memory loss or confusion while taking D! Coumadin ) to remember that statins are not the only treatment for high cholesterol to lower total., making it more powerful harmful to the body treatment for high cholesterol to lower their cholesterol... Association, it does n't mean that you ca n't take a statin that minimizes potential drug interactions, on! Often prescribe statins for people with high cholesterol out what the total cost of the FDA-authorized 5-day of. Does contain compounds that alter how your body and Get rid of your health problems proceeds Web... And decreasing your risk for heart disease: Everything you need to take them safely 5-day course ritonavir-boosted! To select a statin that minimizes potential drug interactions, depending on which medications 're... Them just in case library of archived content make nerve endings more sensitive pain...: what medications may cause some risk when taken together nonsteroidal anti-inflammatory drugs ( )... Cyclosporine and ibuprofen, your doctor should take this into account if you have decreased kidney function over-the-counter... Eating nuts for heart disease readers, Harvard health Publishing provides access to library! Oral contraceptive while taking vitamin D and calcium supplements may help to prevent fractures, they can also lead kidney. Medications: statins of a heart attack or stroke drug-induced diabetes mellitus: Evidence for statins other...